By Ian Stuart-Hamilton
With the world's inhabitants getting more and more older, there hasn't ever been a extra urgent want for the learn of previous age and ageing. An advent to Gerontology offers a wide-ranging advent to this significant subject. via assuming no earlier professional wisdom and averting jargon, this publication will advisor scholars via all of the major topics in gerontology, overlaying either conventional parts, comparable to organic and social growing old, in addition to extra modern components, comparable to know-how, the humanities, sexuality and schooling of older adults. An advent to Gerontology is written through a group of overseas authors with multidisciplinary backgrounds who draw facts from various diversified views and traditions.
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Paradoxically, it is conventional wisdom that women have poorer health than men, though sex differences in morbidity suggest the situation to be more complex than conventional wisdom suggests, with strong variation observed across the lifespan (Macintyre, Hunt and Sweeting, 1996). 2). 12 on Thu Oct 11 11:23:13 BST 2012. 002 Cambridge Books Online © Cambridge University Press, 2012 23 24 ˜ Pedro de Magalhaes ˜ Joao progressively more likely to die (Medawar, 1952). 2, human mortality rates increase exponentially after about age 30.
Overall, although ROS might well play a role in agerelated pathologies, there is little evidence that they are at the root of the ageing process. One crucial molecule in life is DNA. Given its central role in directing cellular functions and in the creation of the cell itself, damage to the DNA can be catastrophic. The physicist Leo Szilard first proposed the idea that a slow build-up of damage in the DNA could gradually disrupt normal cellular functions and result in ageing (Szilard, 1959). , 1989).
002 Cambridge Books Online © Cambridge University Press, 2012 27 28 ˜ Pedro de Magalhaes ˜ Joao ageing between individuals of the same species. In particular, experiments in model organisms have demonstrated that ageing can be manipulated by genetic and environmental factors. Understanding the mechanisms involved might allow human ageing to be manipulated. As such, the discoveries detailed below on the plasticity of ageing are among the most important in our understanding of the biology of ageing.
An Introduction to Gerontology by Ian Stuart-Hamilton