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Extra resources for Basic Science for Core Medical Training and the MRCP

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Phospholipids contain a charged tail and hydrophobic head. C. The asymmetric distribution of phospholipids between the cytosolic and extracellular face is maintained by an enzyme called ‘flippase’. D. Carbon dioxide can diffuse readily across the plasma membrane. E. Polytopic proteins completely cross the membrane. 3. Which of the following is a non-membrane bound organelle, which degrades proteins targeted by ubiquitylation? Endosomes. Lysosomes. Proteasomes. D. Endoplasmic reticulum. E. Golgi apparatus.

The linking of these three pathways by production of a common end-product allows integration of several different energy sources to provide an uninterrupted supply during a wide variety of activities and situations. The basic processes occurring in the body can be broadly divided into catabolic reactions, where energy is released from a molecule during degradation, often involving the oxidation of fuel molecules, and anabolic reactions ultimately leading to the synthesis of new molecules. Metabolism can be defined as the combination of these two processes.

Interphase can be divided into three distinct phases: G1, S, and G2. 2). The cycle can be arrested between G1 and S at the G1 restriction checkpoint by modulation of cyclin-dependent kinase activity (for example, by retinoblastoma protein, RB1) if environmental conditions do not favour cell division. By the end of the short-lasting S phase, DNA replication is complete and two Chapter 2 Cellular, molecular, and membrane biology Ribosome mRNA duplicates of each chromosome (chromatids) exist, bound together at the centromere by cohesins.

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Basic Science for Core Medical Training and the MRCP by coll.


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