By Gerhardus de Jong

ISBN-10: 3527339248

ISBN-13: 9783527339242

ISBN-10: 3527693807

ISBN-13: 9783527693801

ISBN-10: 3527693815

ISBN-13: 9783527693818

ISBN-10: 3527693823

ISBN-13: 9783527693825

ISBN-10: 3527693831

ISBN-13: 9783527693832

This monograph deals the reader a whole evaluate on either rules and purposes of CE-MS. beginning with an introductory bankruptcy on detection in CE, additionally comparable and extra really expert ideas corresponding to electrophoretic and chromatographic preconcentration are mentioned. a distinct emphasis is wear CE-MS interfaces, that are defined intimately. In a separate bankruptcy, recognition is paid to sheath-liquid interfacing. The advancements and probabilities of microchip CE-MS also are defined. functions to all proper parts are mentioned in distinctive chapters, each one written via specialists within the respective fields.
along with functions in pharmaceutical research and bioanalysis, contemporary implementations in nutrition technology, forensic research, research of intact proteins, metabolomics and proteomics are highlighted. MS is a wonderfully acceptable detection process for CE, as effective separation is coupled to delicate and choice detection. in addition, MS supplies constitution info at the separated compounds. CE-MS has now been built right into a robust hyphenated procedure complementary to LC-MS. This monograph is an particular resource of data for everybody facing and drawn to CE-MS

Show description

Read Online or Download Capillary Electrophoresis - Mass Spectrometry (CE-MS) Principles and Applications PDF

Best analytic books

Protein Folding, Misfolding and Aggregation

This targeted e-book covers all of the glossy techniques and the numerous advances skilled within the box over the last 10 years. there's a lot emphasis on computational equipment and reviews of protein aggregation that have particularly flourished within the final decade. It contains chapters within the parts that experience witnessed significant advancements and written via most sensible specialists together with: computing device simulations of folding, speedy folding, unmarried molecule spectroscopy, protein layout, aggregation stories (both computational and experimental).

Separation Techniques in Clinical Chemistry

This reference examines recommendations in separation technology for better sensitivity and cost-efficiency, elevated pace, larger pattern throughput and decrease solvent intake within the review, assessment, and validation of rising drug compounds. It investigates breakthroughs in pattern pretreatment, HPLC, mass spectrometry, capillary electrophoresis and healing drug tracking for enhanced productiveness, precision, and protection in scientific chemistry, biomedical research, and forensic learn.

Digital Simulation in Electrochemistry

This publication is an in depth revision of the sooner booklet with a similar identify, 1981. The reader who has the 1st version will realize chapters 1-3 and components of Chapt. four; thereafter, there's little similarity. There are numerous purposes for this. to start with, as one inner Danish e-book acknowledged, the 1st version contained "et hav af smafejl" that means (with a few poetic license), a sea of issues.

Extra resources for Capillary Electrophoresis - Mass Spectrometry (CE-MS) Principles and Applications

Sample text

2011) Dating silk by capillary electrophoresis mass spectrometry. Anal. , 83, 7577–7581. 39 41 3 Sheath Liquids in CE-MS: Role, Parameters, and Optimization Christian W. 1 Introduction Only 6 years after the first paper on capillary electrophoresis (CE) by Jorgenson and Lukacs in 1981 [1], Smith’s group described the coupling of CE with mass spectrometric detection (MS), using an interface without a sheath flow [2]. Just 1 year later, the same group presented an improved electrospray ionization (ESI) interface for CE-MS, this time involving the use of a sheath liquid (SL) [3].

85. 86. profiling of intact pharmaceutical proteins. Anal. , 85, 2289–2296. Y. (2012) Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis–tandem mass spectrometry. J. Chromatogr. A, 1267, 162–169. , and Li, L. (2015) Relative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS. Analyst, 140, 467–475. , and Hankemeier, T. (2014) Capillary electrophoresis–mass spectrometry using a flow-through microvial interface for cationic metabolome analysis.

2010) Mass spectrometry and glycomics. OMICS, 14, 401–418. M. et al. (2013) Coupling porous sheathless interface MS with transient-ITP in neutral capillaries for improved sensitivity in glycopeptide analysis: CE and CEC. Electrophoresis, 34, 383–387. W. (2013) Low-flow sheathless capillary electrophoresis–mass spectrometry for sensitive glycoform References 79. 80. 81. 82. 83. 84. 85. 86. profiling of intact pharmaceutical proteins. Anal. , 85, 2289–2296. Y. (2012) Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis–tandem mass spectrometry.

Download PDF sample

Capillary Electrophoresis - Mass Spectrometry (CE-MS) Principles and Applications by Gerhardus de Jong


by Charles
4.5

Rated 4.17 of 5 – based on 46 votes